Oct-7-yn-1-yl-4-methylbenzenesulfonate-生命科学试剂-MCE.pdfVIP

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Inhibitors•ScreeningLibraries•Proteins

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Oct-7-yn-1-yl4-methylbenzenesulfonate

Cat.No.:HY-W877039

CASNo.:219982-82-8

分⼦式:C₁₅H₂₀O₃S

分⼦量:280.38

作⽤靶点:PROTACLinkers

作⽤通路:PROTAC

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性Oct-7-yn-1-yl4-methylbenzenesulfonate是⼀种PROTAClinker，可⽤于合成PROTAC分⼦。

体外研究PROTACscontaintwodifferentligandsconnectedbyalinker;oneisaligandforanE770ubiquitinligase

andtheotherisforthetargetprotein.PROTACsexploittheintracellularubiquitin-proteasomesystemto

selectivelydegradetargetproteins.

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Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

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