N-Palmitoyl-l-leucine-GK144-生命科学试剂-MCE.pdfVIP

Hotline:400-820-3792

Inhibitors•ScreeningLibraries•Proteins

www.MedChemE

N-Palmitoyl-l-leucine

Cat.No.:HY-122756

CASNo.:14379-42-1

Synonyms:GK144

分⼦式:C₂₂H₄₃NO₃

分⼦量:369.58

作⽤靶点:Phospholipase

作⽤通路:MetabolicEnzyme/Protease

储存⽅式:Powder-20°C3years

4°C2years

Insolvent-80°C6months

-20°C1month

BIOLOGICALACTIVITY

⽣物活性N-Palmitoyl-l-leucine(GK144)是⼀种分泌型磷脂酶A2(secretedphospholipasesA2)抑制剂。N-Palmitoyl-l-

leucine可⽤于炎症性疾病的研究[1]。

IC50TargetsPLA2

REFERENCES

[1].MouchlisVD,etal.InhibitionofsecretedphospholipasesA₂by2-oxoamidesbasedonα-aminoacids:Synthesis,invitroevaluationand

moleculardockingcalculations.BioorgMedChem.2011Jan15;19(2):735-43.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

Tel:400-820-3792;021Fax:021E-mail:tech@MedChemE

1/1