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- 2026-02-06 发布于上海
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Inhibitors•ScreeningLibraries•Proteins
www.MedChemE
NVP-LBX192
Cat.No.:HY-14172
CASNo.:866772-52-3
分⼦式:C₂₆H₃₃N₅O₄S₂
分⼦量:543.7
作⽤靶点:Glucokinase
作⽤通路:MetabolicEnzyme/Protease
储存⽅式:Pleasestoretheproductundertherecommendedconditionsin
theCertificateofAnalysis.
BIOLOGICALACTIVITY
⽣物活性NVP-LBX192(Compound17c)是⼀种葡萄糖激酶(glucokinase)激活剂，其K(a)值为39nM。NVP-LBX192
能显著降低⾎糖⽔平。NVP-LBX192可⽤于代谢性疾病的研究，如2型糖尿病[1]。
REFERENCES
[1].BebernitzGR,etal.Investigationoffunctionallyliverselectiveglucokinaseactivatorsforthetreatmentoftype2diabetes.JMedChem.
2009Oct8;52(19):6142-52.
McePdfHeight
Caution:Producthasnotbeenfullyvalidatedformedicalapplications.
Forresearchuseonly.
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