Oberadilol-CID-3047798-生命科学试剂-MCE.pdfVIP

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Oberadilol

Cat.No.:HY-19088

CASNo.:114856-44-9

Synonyms:CID-3047798

分⼦式:C₂₅H₃₀ClN₅O₃

分⼦量:483.99

作⽤靶点:Phosphodiesterase(PDE);AdrenergicReceptor

作⽤通路:MetabolicEnzyme/Protease;GPCR/GProtein;Neuronal

Signaling

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性Oberadilol(TZC5665)是⼀种强效且选择性的PDE-III抑制剂。Oberadilol具有⾮选择性的β-肾上腺素受体阻

断作⽤。Oberadilol表现出负性变时性和负性变⼒性作⽤。Oberadilol可⽤于充⾎性⼼⼒衰竭的研究[1]。

IC50TargetPDEⅢβ-adrenoceptor

REFERENCES

[1].ImranM,etal.Studyofvariouspyridazineandphthalazinedrugswithdiversetherapeuticalandagrochemicalactivities[J].Russian

JournalofBioorganicChemistry,2020,46(5):745-767.

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