持续正加速度对实验性大鼠胃溃疡愈合质量的影响.docVIP

wcjd@  ?  世界华人消化杂志 2013年7月8日; 21(19): 1841-1846 ISSN 1009-3079 (print) ISSN 2219-2859 (online) 研究快报 RAPID COMMUNICATION 持续正加速度对实验性大鼠胃溃疡愈合质量的影响 陈 璐, 陈 英, 范 勤, 韩全利, 唐合兰, 李 静, 杨春敏  陈璐, 陈英, 范勤, 韩全利, 唐合兰, 李静, 杨春敏, 安徽医科 大学中国人民解放军空军总医院临床学院东楼消化科 北京 市 100142 陈璐, 在读硕士, 主要从事航空航天与航海医学消化系统方面的 研究. 全军十二五后勤科研计划基金资助项目, No. AKJ11J004 作者贡献分布: 陈璐与杨春敏对此文所作贡献均等; 此课题由杨 春敏与陈璐设计; 研究过程由陈璐操作完成; 研究所用试剂及工 具由陈英、范勤、韩全利及李静提供; 数据分析由陈璐与唐合 兰完成; 本论文写作由陈璐完成. 通讯作者: 杨春敏, 主任医师, 100142, 北京市海淀区阜成路30 号, 安徽医科大学中国人民解放军空军总医院临床学院东楼消 化科. chunmyang@ 电话: 010收稿日期: 2013-04-10 修回日期: 2013-05-17 接受日期: 2013-05-25 在线出版日期: 2013-07-08 Effect of persistent positive acceleration on the quality of ulcer healing in rats with experimental gastric ulcer Lu Chen, Ying Chen, Qin Fan, Quan-Li Han, He-Lan Tang, Jing Li, Chun-Min Yang Lu Chen, Ying Chen, Qin Fan, Quan-Li Han, He-Lan Tang, Jing Li, Chun-Min Yang, Department of Gastroenter- ology, East Building, General Hospital of Air Force of Chi- nese PLA, Anhui Medical University, Beijing 100142, China Supported by: the Military Scientific and Technologi- cal Project during the “Twelfth Five-year” Period, No. AKJ11J004 Correspondence to: Chun-Min Yang, Chief Physician, De- partment of Gastroenterology, East Building, General Hospi- tal of Air Force of Chinese PLA, Anhui Medical University, 30 Fucheng Road, Haidian District, Beijing 100142, China. chunmyang@ Received: 2013-04-10 Revised: 2013-05-17 Accepted: 2013-05-25 Published online: 2013-07-08 Abstract AIM: To investigate the effect of positive accel- eration (+Gz) on gastric ulcer healing in rats and to explore the possible mechanisms involved. METHODS: Thirty-two male SD rats were ran- domly and equally divided into a control group, a +5Gz exposure group, a +10Gz exposure group, and a +10Gz exposure plus KangFuXin solution group. Gastric ulcer was induced in rats with ace- tic acid. After 3 d, rats in the latter three groups were exposed to +Gz each other day for 1 wk  (four times in all, five minutes each time).