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代礼 朱军 吴艳乔 周光萱 王艳萍 缪蕾
! 1987~ 1992 ,
, 28
7 d () 4 489 692 ,
94 , 02 1/ , 020/ , 023/
020/ 69 , 536% 468% ,
( 160% ) ( 580% )
, ,
! ; ;
Epidemiological investigation of perinatals affected by transverse facial cleft in China DA I Li, ZH U
Jun, WU Yanqiao, ZH O U Guangx uan, WA N G Yanp ing , MIA O Lei National Center f or Birt
Def ects M onitoring , t e West C ina Second Hosp ital, Sic uan University , C engdu 610041, C ina
Abstract! Objective T o study t he epidemiolo ical features of transverse cleft and its multiple
con enital anomaly ( MCA) patterns in ChinaMethods From 1987 throu h 1992, hospitalbased cluster
samplin method was adopted for collectin dataDurin that period all live or stillbirths wit h 28 weeks of
estat ion or more were assessed w ithin 7 days after delivery Results 94 cases of transverse facial cleft
w ere ident ified amon 4 489 692 births, so the prevalence rate of transverse facial cleft at birth was 021/
4 4 4
10 The prevalence rates in urban areas and in rural areas w ere 020/ 10 and 023/ 10 , respectivelyAnd
4
t he rates in male and female births w ere both 021/ 10 69 cases occurred wit h ot her malformations,
amon which the anomalies of ear were the most frequent associat ion( 536% ) The perinatal fatality rate
w as 469% , a si nificant difference of fatality rate was found between isolated forms ( 160% ) and
associated forms of transverse facial cleft ( 580% ) Conclusions The prevalence rate of transverse facial
cleft in China is more t han the estimated rate No si nificant differences are found between urban and rural
areas, and betw een male and female births Most of transverse facial clefts
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