鲍曼不动杆菌流行病学和治疗策略.pptVIP

2008年CHINET耐药监测革兰阴性菌菌种分布 2007-8本院住院患者病原菌分离种类 2010年鲍曼不动杆菌在各病区分布 Acinetobacter spp Skin Colonization Acinetobacter outbreaks 1977-2000 Acinetobacter outbreaks 1977-2000 Evidence for Airborne Transmission of Acinetobacter Sedimentation plates placed in 7 patients’ rooms with respiratory infection or colonization Acinetobacter Transmission in the Hospital SettingColonization of Healthcare Workers Outbreak of multidrug resistant A. baumanii in a Dutch ICU involving 66 patients with an epidemic strain Nursing staff were cultured (nares axilla, same swab) 15 nurses found to harbor epidemic strain All were culture negative when re-cultured (nose, throat, axilla, perineum) Time to Nosocomial BSI Source of A. baumanii Nosocomial Bloodstream Infection Inflammatory Response to A. baumanii Nosocomial Bloodstream Infection Impact of Acinetobacter Infection in the ICU: historical cohort study Impact of A. baumanii Ventilator-Associated Pneumonia in the ICU Antibiotic ResistanceCommunity vs. Hospital Acquisition Comparison of A. baumanii isolates obtained from the hands of homemakers to isolates obtained from 2 US hospitals 23/222 (10.4%) homemakers had A.baumanii isolated from hands 2007-8鲍曼不动杆菌（本院） Polymyxin antibiotics 谢谢您的关注！ In one study, hands of 131 healthcare workers (HCWs) were cultured before, and hands and gloves after, routine care. A mean of 56% of body sites and 17% of environmental sites were VRE positive. After touching the patient and environment, 75% of ungloved HCWs hands and 9% of gloved HCWs hands were contaminated with VRE. After touching only the environment, 21% of ungloved and 0 gloved HCWs hands were contaminated. The inanimate environment plays a role in facilitating transmission of organisms. A 3-year, prospective, controlled, quasi-experimental study was conducted in 3 ICUs for a 1-year period before a multifaceted infection control intervention (period 1), a 1-year period after the intervention (period 2), and a 1-year follow-up pe