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! 412 ! (Chin J New Drugs Clin Rem) , 2001 11 , 20 6
f iliated H osp ital of Beij ing Medical Unirersity, qd) and fiftysix patients received benazepril ( 10 mg,
BEIJING 100034, C ina; 3 . Dep artment of Car p o, qd) for 8wk. Another 33 patients in open trial
diology, Union H osp ital, Wu an Tongj i Medical received doxazosin with 24 h ambulatory blood pres
University, Wu an H UBEI 430022 , C ina) sure monitoring (ABPM) before and after treatment
4 mg, po , qd for 8 wk. RESULTS: The blood
[KEY WORDS] doxazosin; benazepril; hyperten pressure significantly decreased after treatment with
sion; blood pressure determination; blood pressure doxazosin and benazepril and the effective rates were
monitors; randomized controlled trials; doubleblind 81% and 77 %, respectively at the end of 8wk. And
method the adverse reactions were 3 % and 20 % with no or
thostatic hypotension.24h ABPM showed significant
[ABSTRACT] AIM: To evaluate the efficacy and ly daytime and nighttime blood pressure smoothly re
safety of doxazosin controlled release tablets in pa duction and T/ P ratio: SBP: 0. 69, DBP: 0. 59.
tients with mild to moderate essential hypertension. C NCLUSI N: Doxazosin controlled release tablets
METH DS: A multicenter, doubleblind, double is an effective, safe and longacting 1receptor block
similarly randomized parallel study was designed. er and has less adverse reaction than benazepril in
Fiftyeight patients received doxazosin ( 4 mg, p o, treating mild to moderated essential hypertension.
(Chin J New Drugs Clin Rem) , 2001 11 , 20(6) :412- 414.
2 SOD LPO
王 军, 张金盈 ( , 450052)
[] 果糖二磷酸盐类; 果糖二磷酸钠; 非胰岛 [] 2001
素依赖型糖尿病; 血液流变学; 超氧化物歧化酶; 过
氧化脂质类 2
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