LDL2聚乳酸夹板行下颌骨骨折内固定的实验研究.pdfVIP

　·286　　 · 　口腔颌面外科杂志 　2002 年 第 12 卷 第 4 期 　 论　　著 L/ DL聚乳酸夹板行下颌骨骨折内固定的实验研究 陈宇轩 , 　吕春堂 , 　周树夏 , 　熊成东 　　摘 　要 : 目的　观察国产新型 L/ DL聚乳酸与DL聚乳酸接骨装置行骨折内固定的效果 ,并比较两种可吸收 材料的性能。方法 　用 L/ DL聚乳酸及DL聚乳酸接骨板、螺钉固定 16 只狗下颌骨骨折 ,作同体对照研究。采用 大体、组织学、X 线摄片、骨力学测试及材料理化性能检测等方法 ,观察 2 、4 、8 、20 周时的内固定效果及材料降解吸 收情况。结果 　所有狗双侧下颌骨骨折皆在对位良好的情况下愈合。L/ DL聚乳酸夹板固定侧骨力学强度在 4 、8 ( ) 周时高于 DL聚乳酸夹板固定侧 P 0. 05 。L/ DL聚乳酸的降解吸收较 DL聚乳酸慢 ,对机械强度的保持优于 DL聚乳酸。结论 　L/ DL聚乳酸及DL聚乳酸接骨板、螺钉均能保证下颌骨骨折的愈合 ,符合骨折内固定的生物 力学原则。L/ DL聚乳酸有较高的机械强度 ,更适合于向小型化发展。 　　关键词 : 聚乳酸 ; 内固定;下颌骨骨折 ;生物降解 ;可吸收 　　中图分类号 : R318. 08 　　　文献标识码 : A 　　　文章编号 : (2002) BIOABSO RBABL E PLATES AND SCREWS FO R INTERNAL FIXATIO N OF MANDIBULAR FRACTURE IN DO GS CHEN Yuxuan , LU Chuntang , ZHOU Shuxia ( Department of Stomatology , 252 nd Hospital of PLA , B aoding 071000) 　　Abstract : Objective 　To investigate the internal fixation effects of poly (L/ DLLactide) and poly (DLLactide) frac ture fixation devices. Methods 　After mandibular body fracture models were created in 16 dogs , the right were fixed with poly (L/ DLLactide) plates and screws , the left with poly (DLLactide) plates and screws. The dogs were scarifited at 2 , 4 , 8 and 20 weeks after operation. Gross , radiographical , histologic and bony mechanics examinations of the fracture site were taken immediately after dogs were sacrificed at different time point . Results 　Bony union of both sides was good and the consolidation of fixed osteotomies seemed to be faster in poly (L/ DLLactide ) group than in the poly (DLLactide