浮小麦质量控制探讨.docVIP

浮小麦质量控制探讨 陈小红 （江苏省淮安食品药品检验所，淮安223300） 摘要 目的：考察浮小麦中的农药残留量、重金属及有害元素，建立测定浮小麦中棉籽糖及葡萄糖的HPLC法。方法：参照《中国药典》2010年版一部附录方法检测浮小麦中的农药残留量及重金属及有害元素。选用Phenomenex Luna NH2柱，以乙腈-水（:30）流动相，流1.0ml·min-1，柱温0℃，，℃，测定两种糖的含量。结果：药材中含有有机氯类农药残留量及铅、镉、砷、汞、铜等重金属及有害元素的量较低。棉籽糖在～μg范围内线性关系良好平均回收率%（%）在～μg范围内线性关系良好 平均回收率%（%）。uality control discussion of Fructus Tritici Levis Chen Xiaohong (Huaian Institute for Food and Drug Control ,Huaian 223300) Abstract Objective:To investigate the pesticide residues ,heavy metals and harmful elements ,and establish an HPLC method for the determinations of cottonseed sugar and glucose of Fructus Tritici Levis. Methods: Pesticide residues , heavy metals and harmful elements were investigated according to Chinese Pharmacopoeia 2010 Edition Volume I Appendix .The contents of cottonseed sugar and glucose were determined by HPLC method which were equipped with a NH2 column, acetonitrile–water(70:30) as the mobile phaseat the flow rate of 1.0ml·min-1，column temperature was 30℃;RID was used and the detection pool temperature was 40℃. Results: The contents of several organochlorine pesticide residues and Pb,Cr,As, Hg,Cu and other heavy metals and harmful elements were lower. The linearity of cottonseed sugar was obtainted in the range of 2.35-46.92μg,the average recovery was 101.0%( RSD = 2.0%); the linearity of glucose in the range of 12.30-123.02μg,the average recovery was 98.8%( RSD =1.6%). Conclusion：The established methods are simple and accurate, and can be applied to ensure the quality of medicines and provide the basis for the clinical medication. Key words: Fructus Tritici Levis; pesticide residues; heavy metals and harmful elements; cottonseed sugar; glucose; HPLC. 浮小麦为禾本科(Gramineae)小麦Triticum aestivum L.以粒匀、轻浮，表面有光泽者为佳。充实饱满的小麦粒，不宜作浮小麦入药[]。浮小麦化学成分报道较少 5-heneicosyresorcinol )和亚油酸[2]。普通小麦含淀粉蛋白质糖类(蔗糖、葡萄糖、棉糖、麦芽糖、蜜二糖)糊精脂肪油等尚含少量谷甾醇( Sitosterol )、卵磷脂( Lecithin )、尿囊素( Allantoin )、氨基酸类、维生素B等[]。糖类是自然界中最知名的一种三糖，由半乳糖、果糖和葡萄糖结合而成，可以调节肠道内细菌平衡，恢复肠壁原状并形成保护层，保护肠道健康。能够防止肠道内