HFOV治疗新生儿严重肺疾病合并呼吸衰竭的临床观察.pdfVIP

376 Journal of Medical Science in Central South China,July2012,Vol.40,No.4 文章编号:2095-1116(2012)04-0376-05 ·临床医学· HFOV治疗新生儿严重肺疾病合并呼吸衰竭的临床观察 吴州丽,谭摇 宁,朱文军 (郴州市第一人民医院北院新生儿科,湖南郴州423000) 摘摇 要:摇 目的摇 回顾性观察比较高频振荡通气(HFOV)和常频通气治疗新生儿严重肺疾病合并呼吸衰竭的 有效性及安全性。 摇 方法摇 HFOV组79例,常频组80例,观察对比两组治疗前后氧合参数、呼吸机参数、治愈率、 上机天数、住院天数以及并发症等的差异。 摇 结果摇 HFOV组治疗6 h后通气氧合情况明显好转,氧指数(OI)下降 至8.82依3.98(P0.05),动脉血氧分压(PaO )升高至73.88依17.03 mmHg(P0.05),二氧化碳分压(PaCO )下 2 2 降至38.51依5.03 mmHg(P0.05),治疗24 h后氧浓度(FIO )、OI 明显降低,上机天数缩短,并发支气管肺发育不 2 良(BPD)及气漏减少,与常频组比较差异有统计学意义(P 0.05)。 摇 结论摇 HFOV 治疗新生儿严重肺疾病合并 呼吸衰竭氧合改善更快,短时间内氧浓度及OI下降更快,上机天数缩短,并发BPD、气漏减少,临床疗效满意。 关键词:摇 高频振荡通气;摇 常频通气;摇 新生儿;摇 严重肺疾病;摇 呼吸衰竭 中图分类号:R722郾135摇 摇 摇 文献标识码:A The Clinical Observation of High Frequency Oscillatory Ventilation in the Treatment of Neonatal Severe Lung Disease Complicated With Respiratory Failure WU Zhouli,TAN Ning,ZHU Wenjun (Neonatal Department,the First People爷s Hospital of Chenzhou,Chenzhou,Hunan423000,China) Abstract:摇 Objective摇 To contrast the validity and security of treating neonates severe lung disease complicated with respiratory failure,betweenhighfrequencyoscillatoryventilation (HFOV)andconventionalmechanicalventilation(CMV).摇 Methods摇 79 patientsweretreated by HFOV,80 patientsweretreated by conventional mechanical ventilation (CMV),there were differences intheoxygenateparameter,respiratoryparameter,thecurerate,ventilatorsupportdays,lengthof stay,compli鄄