多模式CT 指导与动脉溶栓术对急性脑梗死与疗效研究.docVIP

多模式CT指导的动脉溶栓术对急性脑梗死的疗效研究 马 海1 ，陈康宁2 ，任亚静1 ，刘连锋1 (1712000陕西 咸阳，中铁二十局中心医院神经内科；2400038重庆，第三军医大学西南医院神经内科) [摘要]目的 观察多模式CT指导下的动脉内rt-PA接触溶栓的疗效。方法 2010年6月至2012年6月于我院就诊，经多模式CT筛选出符合溶栓的患者32例。分为＜3h及3-6 h组。记录溶栓前、后的NIHSS、MRS及BI评分。结果 32例样本中26例(81.2%)患者溶栓治疗有效，23例(71.9%)临床结局良好，16例(50.0%)血管完全再通，症状性出血1例(3.1%)。加：… 结论 多模式CT指导的动脉溶栓术是一种有效可行的治疗方法。 [关键词] 脑梗死；动脉溶栓术；头颅CT Study of application of multimode CT evaluation in the artery thrombolytic therapy after stoke MA Hai et al （1Department of Neurology， Chinese Railway 20 Part Central Hospital，shanxi xianyang，712000；2Department of Neurology, Southwest Hospital, Third Military Medical University, Chongqing, 400038, China） [Abstract] Objective To observe the efficiency and safety of the application of muhimode CT evaluation in intra-arterial thrombolytic therapy with recombinant tissue plasminogen activator(rt-PA).Methods： From June 2010 to June 2012 patients within6h after stroke who visited our hospital were randomly recruited．Using multimode CT evaluation,32 patients eligible to receive intra-arterial thrombolytic therapy with rt-PA were found and treatment to them within3 h or 3-6 h after onset of ischemic stroke were given．Their mRS．NHISS and B1 were scaled and recorded before and after intra-arterial thrombolytic therapy．Results：After rt-PA treatment．26 of 32(81.3％)patients had increased clinical activity．Faivorable outcome rate of patients was 71.9％．Sixteen patients(50％)had recanalization in the occluded arteries after rt-PA treatment．There was l patient(3.1％)having symptomatic intracranial hemorrhage(ICH)in onr study．NIHSS, mRS and BI score was improved after thrombolytic therapy.The difference between two groups on safety was no statistical significance difference．Conclusion ：Multimode CT evaluation in the rt-PA therapy is an useful tool to select eligible patients after acute ischemic stroke to have intra-arterial thrombolytic therapy with rt-PA [Key words] acute cerebral infarction; intra-arterial thrombolysis ; 对于急性脑梗死，