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The Concentration effect and the Second gas effect Anesthesiology:SunBo The solubility of blood Factors Affecting Alveolar Concentration (FA) Cause of the concentration effect If 50% of an anesthetic is taken up by the pulmonary circulation, an inspired concentration of 20% (20 parts of anesthetic per 100 parts of gas) will result in an alveolar concentration of 11% (10 parts of anesthetic remaining in a total volume of 90 parts of gas). if the inspired concentration is raised to 80% (80 parts of anesthetic per 100 parts of gas), the alveolar concentration will be 67% (40 parts of anesthe
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