ACE基因多态性与急性缺血性中风始发证候相关性的研究.pdfVIP

辽宁中医杂志 2008年第 35卷第 4 期 481 ACE , , ( 广东省中医院, 广东 广州 5 10 120) : 目的: 探讨 ACE 基因多态性与急性缺血性中风始发证候的相关性方法: 选择发病 7 天之内急性缺血性中 风患者 118 , 进行 ACE 基因( D / I) 多态性检测, 同时进行证候分型, 分析两者之间的相关性结果: 单因素分析结果显 示, 非 II型痰证比 明显升高, 2 非 DD型气虚证比 明显升高, 2 = 0. 036; 组间比较 = 4. 882, P = 0. 036; = 4. 750, P 有统计学意义结论: D 等位基因与痰证I等位基因与气虚证的发生可能存在相关性 : ACE 基因多态性; 急性缺血性中风; 始发证候 : R743. 3 : B : 1000- 1719( 2008) 04- 0481- 03 Exploration on theRelevance of the ACE Gene Polymorphism and Acute Ischem ic Stroke Predicate Syndrom e J IA N i, YOU J in - song, H UANG P e i- x in ( Guang dong P rov inc ialH o sp i al of TCM , Guangzhou 510120, Guang dong, Ch ina) Abstract: O bj ec iv e: Exp lor th ACE g n polym orph ism and acut isch m ic strok pr d icat syndrom r l vanc . M e hod s: Th incid nc w ithin s v n days of acut isch m ic strok pati nts w ith 118 cas s, th ACE g n ( I / D) polym orphism d t ction, smi u ltan ously syndrom typ ing, analysis b wt n th wt o r l vant. R esul s: Un ivariat analysis show d that non- c r 2 tifi d Typ II sputum ratio incr as d significantly, = 4. 882, P = 0. 036; Non - DD- d fici ncy syndrom s ratio incr as d 2 significantly, = 4. 750, P = 0. 036; Diff r nc s b tw n th groups w as statistically significanc . C onclus ion : D all l and sputum card, I all l and th incid nc of d fici ncy syndrom s possib l r l vanc . K eywords: ACE g n polym orphism; acut isch m ic strok ; pr d icat syndrom - , 1. 2 诊断标准 Ang RAS : 1996 ( Angiot nsin Con v rting Enzym , ACE), Ang IACE [ 2]