高容量血液滤过对多器官功能障碍综合征患者降钙素原影响的.pdfVIP

·12· ·论著· 高容量血液滤过对多器官功能障碍 综合征患者降钙素原影响的初步探讨 肖雄箭林建东 李玮 阙敢波 【摘要】 目的探讨高容量血液滤过(HVHF)对多器官功能障碍综合征(MODS)患者血浆降钙素原 (PCT)的影响。方法选择MODS患者40例，随机分为对照组和HVHF组，对照组采用传统的西医治疗方 法，HVHF组在传统治疗基础上行HVHF治疗，分剐测定2组患者血白细胞总数(wBc)、中性粒细胞(N)百 II评分。比较2组患者的病死率以及存活组和死亡组PCT、A- 分比、血乳酸(Lac一)、血浆PCT以及APACHE PACHE II的差别。结果2组患者治疗前各项指标无差别，对照组经传统西医治疗后5—7d部分指标才开 5—7d各项指标均显著低于对照组(P均0．01)。HVHF组病死率明显低于对照组(P0．05)，分别为 MODS病死率，改善MODS患者预后。 【关键词】 多器官功能障碍综合征； 降钙素原； 高容量血液滤过 Effectof volumehaemofiltrationOil in with hi【gh procalcitoninpatientsmultipleorgandysfunctionsyn- drome．XIAO Can—bo．IntensiveCare First to Xiongqian，LINJian一如，咨，LIWei，QUE Unit，TheHospitalAffiliated Medical Fujian University(n‘舶“350005，China) e仃ectof volume To the 【Abstract】Objectiveinvestigate hiigh haemofihration(HVHF)onplasmaprocal— with 40 withMODS citonin(PCT)inpatientsmultipleorgandysfunctionsyndrome(MODS)．Methodspatients were intocontrol andHVHF control receivedtraditionalwestmedicine divided randomly group group．Thegroup HVHFaswellasthetraditionalwestmedicine cell andtheHVHF received blood therapy group therapy．White APACHE measuredinboth mortali- II (WBC)，neutrophil(N)，PCT，lacticacid(Lac一)andscore，were groups，the in wag andAPACHEwerealso betweenthesurvivalanddead both 11 ty groupscompared．PCT compared group Theaboveindexeshadnodifferencebetweenthe beforethetreatment．Partialindexesinthe group．Results