数值模拟技术应用于颅内动脉瘤生长趋势预测.pdfVIP

数值模拟技术应用于颅内动脉瘤生长趋势的预测 1 1 1 2 1 邱晓宁 刘应征 王炜哲 费智敏 曹兆敏 （1 上海市，上海交通大学机械动力学院叶轮机械研究所，200240 ） （2 上海市，上海交通大学仁济附属医院，200001 ） 摘要：最近的研究显示颅内动脉瘤手术的危险性要大于动脉瘤自身破裂。为了去避免不必要的手术，以及 为手术提供充足的病变区域信息，我们需要充分理解导致动脉瘤的生长和破裂的原因。根据我们得到的动 脉瘤信息可以为手术提供充足的信息。我们知道血液动力学被视为导致动脉瘤生长和破裂的重要因素，例 如血流冲击、瘤腔内压力、壁面剪切力等。本文采用数值模拟的方法分析瘤腔内部的血流参数，通过这些 参数更好的理解动脉瘤的发展趋势。并且以此来预测动脉瘤的生长与破裂区域。 关键词：计算流体力学， 数值模拟， 血液动力学， 颅内动脉瘤 Numerical simulation of intracranial aneurysms growth trends forecast 1 1 1 2 Xiao-Ning Qiu Ying-Zheng Liu Wei-Zhe Wang Zhi-Min Fei Zhao-Min Cao1 （1 Shanghai, Key Lab of Education Ministry of China for Power Machinery and Engineering, Shanghai Jiao Tong University, 200240） (2 China, Renji Hospital, Shanghai Jiao Tong University, 200001,) Abstract:Recent studies have shown that the risk of intracranial aneurysm surgical is much larger than the rupture of aneurysm. In order to avoid the risks of unnecessary surgery, we need to have a better understanding of aneurysm growth and rupture. According to the aneurysm information of our acquired for the aneurysm surgical to provide adequate information. We know that hemodynamic factors deemed to an important factors in aneurysm growth and rupture ，such as blood flow impingement, luminal blood pressure, wall shear stress and so on. In this paper, adopts the method of numerical simulation to analysis the parameters of blood flow in the aneurysm, by means of these data to get a better understand the develop of aneurysm. Moreover predict the growth and rupture of the aneurysm. Keywords: CFD, Numerical simulation, Hemodynamics, Intracranial aneurysm 1、引言 颅内动脉瘤是颅内动脉壁异常突起导致的，他多发于基底动脉和WILLS 环附近的曲率 较大和分叉的部