那格列奈与瑞格列奈治疗2型糖尿病的随机双盲多中心临床的的研究_郑旭琴.pdfVIP

2004 8 4 ·12 · Jour al of Cli ical Medici e i Practice 2 1 1 1 1 1 2 3 4 郑旭琴 , 王晓东, 蒋　琳 , 沈　备, 刘　超 , 徐向进, 刘树琴, 任　安 (1. , , 210029;2. , , 350001;3. , , 230022;4. , , 230001) 　　　:　2 2 。　、 (1 ∶1)、, 14 , 12 。4 233 , (A )117 , (B)116 。　:(HbA1c)、 (2hPBG)、 (FBG) 12 , (P0.05), 2 ( 0.05)。: 12 (TG)(TC), P TG (P0.01), 2 。 12 1 PLT 。4 , 2 , (PLT);2 , ; 1 , 3 , 。。12 , 。　, , 。 :;;2 ;; :R 587.1　　:A　　:1672-2353(2004)04-0012-04 A DOUBLE-BLIND RANDOMIZED CLINICAL STUDY IN MULTIPLE-CENTER COMPARING THE EFFECT OF NATELGINIDE ON TYPE 2 DIABETES WITH REPAGLINIDE 1 1 1 1 1 ZHENGXu-qin , WANG Xiao-dong , JIANG Lin , SHEN B i , LIU Chao , 2 3 4 XU Xiang-jin , LIU Shu-qin , REN An (1.Dep artment of Endocrine, First Af f iliated Hosp ital of N anj ing Medical University, N anj ing, J iangsu, 210029;2.Department of Endocrine, PLA Fuz ou General Hosp ital, Fuz ou, Fuj iang, 350001;3.Department of Endocrine, First Af f iliated Hosp ital of An ui Medical University, Heif ei, An ui, 230022;4.Department of Endocrine, An ui Provincial Hospital, Hef ei, An ui, 230001) 　　ABSTRACT 　Obj ctiv :To evaluate the effect a d safety of ategli ide o type 2 diabetes. M thods:A double-bli d ra domized cli ical study i the multiple-ce ter compariso with the ef- fects of ategli ide o type 2 diabetes a d repagli ide i 2 groups for 14 w eeks of experieme t a d 12 w eeks of observ tio .Rusults:After 12 weeks, ategli ide sig ifica tly reduced the hemoglobi A (1c)(