生姜油提取物对过氧化氢致大鼠肝细胞损伤的保护作用.pdfVIP

2009 8 35 8 Jia g su Med J, Augu st 2009, Vol 35, No. 8 # 937 # # # 沈 洪 顾福萍 张 蓓 毋 涛 = ( H O ) 2 2 A( ) B( ) C( ) 6 SD 6 , 4 ABC , 2 H O , 2 2 ALTAST ( MDA) ( GSH-Px) A ALT AST , MDA , GSH-Px ; B ALT AST , MDA , GSH- Px , ALT A ; C ALT AST , GSH- Px , MDA AST A H O 2 2 , A , = ; ; = R285 = A = 0253-3685(2009) 08-0937-03 Comparison of the protective effects of different extracts of ginger oil on hepatocytes injury induced by hydrogen peroxide in vitro SHEN Ho g, GU Fupi g , ZHANG Bei , et al . Medical Departm e t , Huzhou Teachers College, Huzhou 313000, CHINA = Abstract Obj ective T o compare the protective effects of three parts of gi ger oil ext ract o hepatocytes i jury i duced by hydroge peroxide( H O ) i vitro. Methods The serum-drug trealed 2 2 with three parts of gi ger oil extract w as prepared wit h SD rat s. T he model of hepatocyte i jury i duced by H O w as used to exumi e the effects of t he serum-drug o the act ivities of ala i e 2 2 ami otra sferase ( ALT ) , aspartat e ami otra sferase ( AST ) , malo dialdehyde ( MDA ) a d glutat hio e peroxidase ( GSH- Px) i cultured super ata t. Results Part A of gi ger oil could sig ifica tly decrease the levels of ALT , AST a d MDA, i crease the activity of GSH-Px . Part B also sig ifica tly decreased t he levels of ALT , AST a d MDA, i creased the act ivit y of GSH-Px . H ow ever its effec