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Journal of Pediatric Surgery (2012) 47, 707–714 /locate/jpedsurg Propranolol treatment of infantile hemangioma: clinical and radiologic evaluations a b,⁎ c b Ahmed A. Talaat , Mahmoud S. Elbasiouny , Doaa S. Elgendy , Tarek F. Elwakil a Unit of Clinical Research, Department of Pediatrics, National Research Centre, Cairo, Egypt b Unit of General Surgery, Department of Medical Applications of Lasers, National Institute of Laser Enhanced Sciences (NILES), Cairo University, Cairo, Egypt c Unit of Ultrasonography, Department of Pediatrics, Childrens Hospital, Cairo University, Cairo, Egypt Received 22 June 2011; revised 21 October 2011; accepted 22 October 2011 Key words: Abstract Infantile hemangioma; Background: There is no way to predict the size that proliferative infantile hemangiomas (IHs) can reach Treatment; and to expect the occurrence of complications. Moreover, there are no well-known characteristics that Pharmacotherapy; can affect the rate of involution of IHs and to predict its completion. Accordingly, intervention is Propranolol; frequently indicated. Different modalities have been reported for treatment of IHs. The possible β-adrenergic antagonist mechanisms of action of propranolol on IHs are complex. Methods: Fifty infants presented with 80 IHs treated by oral propranolol at a dose of 2 mg/kg body