川芎油软胶囊治偏头痛(血瘀证)的临床观察.pdfVIP

中文摘要 目的：以安慰剂为对照，进一步评价川芎油软胶囊治疗偏头痛（血瘀证）的 有效性与安全性。 方法：80 例偏头痛患者随机分为治疗组和对照组。治疗组给予川芎油软胶 囊，每次2 粒，每天2 次。对照组给予安慰剂每次2 粒，每天2 次，疗程各12 周。观察川芎油软胶囊的疗效，并对其临床安全性作初步观察。 结果：用药后治疗组和对照组月平均头痛发作次数减少方面比较差异有显著 性（P0.05），中医证候改善治疗组明显优于对照组（P0.05）。治疗组总有效 率为78.69%，对照组总有效率为47.37%，两组比较差异有显著性（P0.05）， 提示治疗组疗效优于对照组。安全性检测，观察患者血尿便常规、心电图、肝肾 功能及不良反应，显示该药无任何毒副作用，使用安全。 结论：川芎油软胶囊通过提高患者的痛阈值，拮抗钙离子，降低血浆粘度， 抑制血小板聚集，改善局部血液循环等多种途径来有效地控制偏头痛发作，减少 发作次数和缩短发作时间，临床治疗偏头痛安全有效。 关键词：偏头痛 中医药疗法 川芎油软胶囊 安慰剂 临床观察 5 ABSTRACT Objective: As compared with placebo, further evaluation of Chuanxiong oil soft capsule in treating migraine (blood stasis) the effectiveness and safety. Methods: 80 patients with migraine were randomly divided into treatment group and the control group. Treatment group Chuanxiong oil soft capsule, 2 each, 2 times a day. Every time the control group given placebo 2, 2 times a day. Course of the 12 weeks. Chuanxiong oil soft capsule to observe the efficacy and safety of a preliminary clinical observation. Results: After the treatment group and control group on the average number of headache attacks and, on average, but the treatment group compared with the control group were significantly different (P 0.05), improvement of traditional Chinese medicine syndromes of the treatment group was significantly better than the control group (P 0.05). The total effective rate was 78.69 percent, control group, the total effective rate was 47.37 percent, a significant difference between the two groups (P 0.05). Efficacy of the treatment group than the control group. Safety testing, observation of patients with hematuria will be conventional, electrocardiogram,