叶黄素补充改善摄入过量大鼠血脂异常及氧化应激状况的研究.pdf

ProtectiveEffetsofLuteinonserumandOxidativeStressin lipids excessiveironintakerats lUlllIIllll IllIlllllllI lUI Abstract isoneoftheessentialtrace excessiron riseflee objetive：Iron elements，but supplementation may radicalsandcauseserum abnormalitiesthat cellsandinterferenormal eventually organ lipid damage function．neaimofthe isto the effectsofluteinonserum and study investigateprotective lipids in iron rats． oxidativestressexcessiveintake were dividedintothe winl12ratsineach SDrats Method：Sixty randomly followinggroups group： rat Fe50 iron Fe1000 control(C)(standardchow,includingmg／kgdiet)，iron(F0)(highdiet，including weFe 1 administration。Animals bw／d(F1，F2，F3)intragastrical mg／kgdiet)，iron+lutein0，20，40mg／kg killedafter6 cholesterol(TC)，lowdensitylipoprotein weeks．Triglyceride(TG)，total andliveriron concentration， cholesterol(LDL-C)，highdensitylipoproteincholesterol(HDL-C)，Serum serum ferritin，total dismutase(T-SOD)，glutathione superoxide detected． malonaldehyde(MDA)were Results：AstheserHm withC LDL—Clevelsincreased TQ lipidsanalysisshowed，compar