PB13206294李树森要点.pptxVIP

Natural molecules and health 李树森 PWhen we had the class which named “chemistry and health”, both of the teachers concentrated on how chemistry influences our health, but chemistry also paly a important role in cure disease. Especially, some natural molecules have wonderful pharmacological. For example, Quinine anhydrous was found to treat malaria in the early 19th century , which comes from cinchona?tree. I am a cinchona?tree. I comes from?the cinchona?tree first , and later was synthetized by many scientists like Woodward who is the father of organic synthesis. Was found in Rauvolfia vomitoria reserpine crystalline（利血平） Rauvolfia vomitoria（催吐萝芙木） This is another example, reserpine crystalline was also synthetized by Woodward . Widely used in the treatment of mild and moderate hypertension ,also used to treated a drop in blood pressure and sometimes as a kind of antipsychotic. People are scared and hopeless when it comes to talk about cancer, but using some natural molecules is one of the versatile methods of curing cancer. Listed herein are some popular natural molecule which can help cure cancer: Paclitaxel(紫杉醇） Camptothecin （喜树碱，CPT） Antroquinonol Oridonin (冬凌草甲素） Paclitaxel M.C. Wani and Monre E. Wall get the separation of the crude extract of taxol from Pacific Yew for the first time in 1963. Taxol is mainly suitable for ovarian cancer and breast cancer , but also has certain curative effect in lung cancer, colorectal cancer, melanoma, head and neck cancer, lymphoma, brain tumors . Antroquinonol Antrodia camphorate （牛樟芝） comefrom Antroquinonol was discovered in 2006, 2007. Correlational? research published in Planta Medica international academic journals. Particularly worth mentioning is Camptothecin is different from other molecules, It is a kind of RAS’s inhibitors , in the other words, it ?prevent?cancer by ?restraining the ?expression of gene. Camptothecin Camptotheca acuminata Decne is only growi