米非司酮与米索前列醇不同用法在重复无痛人工流产术中的应用观察.docVIP

米非司酮与米索前列醇不同用法在重复无痛人工流产术中的应用观察 　　【摘要】 目的：探讨米非司酮与米索前列醇不同用法在重复无痛人工流产术中的应用效果，为米非司酮与米索前列醇不同用法在重复无痛人工流产术中的应用提供科学的理论支持。方法：对2013年1月-2014年12月来笔者所在医院行重复无痛人工流产术的150例患者的临床资料进行回顾性分析，采用完全随机的方法将150例患者分为A、B、C三组，每组50例。其中A组患者于术前晚20∶00口服米非司酮100 mg；B组患者术前2 h于阴道后穹隆放置米索前列醇400 μg；C组患者术前晚20∶00口服米非司酮100 mg的基础上，同时术前2 h舌下含服米索前列醇400 μg，观察米非司酮与米索前列醇不同用法对重复无痛人工流产术患者术前、术中及术后效果等方面的差异。结果：A、B、C三组患者宫颈软化麻醉效果、术后宫颈粘连发生率比较，差异均无统计学意义（P0.05）；C组术前胃肠道不适、手术时间、术中出血量方面与A、B组比较，差异均有统计学意义（P0.05）；A组术后阴道流血时间与B、C组比较，差异均有统计学意义（P0.05）。结论：米非司酮配伍米索前列醇在重复无痛人工流产术中效果优于米非司酮或米索前列醇单独使用，值得在高危人工流产术中进一步推广应用。 　　【关键词】 米非司酮； 米索前列醇； 不同用法； 重复无痛人工流产术 　　中图分类号 R715.2 文献标识码 B 文章编号 1674-6805（2015）31-0024-02 　　【Abstract】 Objective：To study the application effect of Mifepristone combined with Misoprostol in different usage in repeated painless abortion，Mifepristone and Misoprostol for different usage in the application of repeated painless abortion operation to provide scientific theoretical support.Method：From January 2013 to December 2014 to our hospital painless abortion twice of the clinical data of 150 patients were retrospectively analyzed，and were randomly divided into A，B，C group，50 cases in each group.Patients in A group in the preoperative late 20∶00 oral Mifepristone 100 mg.Patients in group B after 2 h in preoperative vaginal fornix placing Misoprostol 400 μg.Patients in C group with preoperative late 20∶00 oral Mifepristone 100 mg，on the basis of preoperative 2 h in sublingual administering Misoprostol 400 μg，observing mifepristone and misoprostol different uses for repeated painless abortion surgery in patients with preoperative，intraoperative and postoperative effect，etc.Result：A，B，C three groups of patients in the cervix softening anesthetic effect，postoperative cervical conglutination of comparative differences had no statistical significance（P0.05）.In C group preoperative gastrointestinal discomfort，operation time，intraoperative blood loss compared with A，B group，the differences were statistically significant （P0.0