奥曲肽联合常规疗法治疗浸润性突眼疗效分析.docVIP

奥曲肽联合常规疗法治疗浸润性突眼疗效分析 　　[摘要] 目的 探讨奥曲肽联合常规疗法治疗浸润性突眼临床效果。 方法 选取该院2013年6月―2104年6月期间收治的54例甲状腺功能亢进浸润性突眼患者作为研究对象，按照随机分组法将其分为对照组和观察组，每组各27例，对照组患者采取常规治疗，观察组患者在常规治疗基础上联合应用奥曲肽进行治疗，治疗疗程均为3个疗程，每个疗程为2个月。 结果 经过有效治疗后，对照组患者显效7例，有效11例，无效9例，总有效率为66.7%，观察组患者显效11例，有效14例，无效2例，总有效率为92.6%，观察组总有效率明显高于对照组，两组比较差异具有统计学意义（P0.05）。 结论 奥曲肽联合常规疗法在治疗甲状腺亢进浸润性突眼方面临床效果明显，该方法值得在临床推广应用。 　　[关键词] 奥曲肽；联合；常规疗法；浸润性突眼；甲状腺功能亢进 　　[中图分类号] R581.1 [文献标识码] A [文章编号] 1674-0742（2015）02（b）-0133-03 　　Infiltrative exophthalmos Efficacy of octreotide conventional therapy 　　DIAO Tingting 　　Ophthalmology， First Affiliated Hospital of Nanyang Medical College，Henan， 473000 China 　　[Abstract] Objective Discussion octreotide conventional therapy infiltrative exophthalmos clinical results. Methods Our hospital in June 2013 - June 2104 were treated 54 cases of hyperthyroidism during infiltrative exophthalmos patients as research subjects， according to the randomization method will be divided into a control group and the observation group， 27 cases in each group， the control patients taking conventional treatment， patients were observed in the conventional treatment based on the combination of octreotide treatment， treatment with a course of three courses， each course of two months. Results After effective treatment， patients in the control group 7 cases markedly effective in 11 cases， 9 cases， the total effective rate was 66.7% of patients in the observation group， 11 cases markedly effective in 14 cases， 2 cases， the total effective rate was 92.6%， was observed The total effective rate was significantly higher， the difference was statistically significant（P 0.05）. Conclusion Octreotide conventional therapy in the treatment of hyperthyroidism infiltrative exophthalmos the clinical effect is obvious， which is worth in clinical application. 　　[Key words] Octreotide； joint； conventional therapy； infiltrative exophthalmos； hyperthyroidism 　　甲状腺功能亢进性浸润性突眼（简称为甲亢浸润性突眼）是甲状腺功能亢进患者常见和较为严重的一种并发症[1]。甲状腺眼疾是一类自身免疫性疾病，主要由淋巴细胞、细胞激素和抗