保心安胶囊治疗气虚血瘀型慢性充血性心衰临床疗效观察.docVIP

保心安胶囊治疗气虚血瘀型慢性充血性心衰临床疗效观察 　　摘要：目的 探讨保心安胶囊联合西药治疗慢性充血性心力衰竭的临床价值。方法 120例慢性充血性心力衰竭患者随机分为两组，各60例。对照组常规综合治疗，单纯给予抗心衰西药西药ACEI、B-受体阻滞剂、螺内酯、利尿剂等，观察组在此基础上增加保心安胶囊，2～3粒/次，3次/d。4 w后对比两组患者临床症状及心功能变化。结果 观察组总有效率93.3%显著高于对照组的80%（P0.05）；治疗后，两组患者心功能分级、NT-proBNP、6分钟步行试验、LVESV、LVESV及LVEF均有不同程度的改善，观察组的改善程度显著优于对照组（P0.05）；两组患者的血压、心率较治疗前均有显著降低（P0.05）。结论 保心安胶囊联合西药治疗气虚血瘀型慢性充血性心力衰竭效果值得肯定，能有效改善患者心室功能，安全可靠，值得临床推广。 　　关键词：保心安胶囊；气虚血瘀型；慢性心力衰竭；疗效观察 　　Clinical Analysis of Baoxinan Capsule in Treating Qi Deficiency-blood Type Chronic Congestive Heart Failure 　　HOU Bao-song，LIU Xia，SONG Yu-qin 　　（Handan Mingren Hospital，Handan 056000，Hebei，China） 　　Abstract：Objective To explore the clinical value of treatment of baoxinanjiaonang combined western medicine chronic in congestive heart failure. Methods 120 patients with chronic congestive heart failure were randomly divided into two groups， 60 cases each. The control group was given routine comprehensive treatment， profess to convincedof western medicine.The observation group on the basis of this， and increase baoxinanjiaonang take 2～3pills every time ， 3 / d.Compared two groups of patients with clinical symptoms and cardiac function changes after 28 d.Results Totaleffectiverate of theobservation group was 93.3%，significantly higher than80% of the control group（P 0.05）； After treatment， cardiac function classification， LVESV， LVESV and LVEF？of two groupswereimproved， the improvement of observation group was superior to that of the control group （P 0.05）；The blood pressure and heart rate were significantly lower than before （P0.05）. Conclusion It’s showed a positive effect of baoxinanjiaonang combined western medicine in patients with chronic congestive heart failure， can improve ventricular function in patients with， safe and reliable，its worthyof promotion. 　　Key words：Baoxinan capsule； Qi Deficiency-blood Type； Chronic heart failure； Clinical observation 　　慢性心力衰竭（Chronic Heart Failure，CHF）是由于心脏泵血功能障碍.出现心排血量不足，组织的血液灌注减少，以及肺循环或体循环静脉系统淤血为特征的临床病理