甲状腺清洁手术是否应用抗生素的临床回顾分析.docVIP

甲状腺清洁手术是否应用抗生素的临床回顾分析 　　【摘 要】目的：探讨甲状腺清洁手应用抗生素与否对切口的感染及愈合情况。方法：对甲状腺手术根据是否应用抗生素，分为观察组和对照组（两组均排除有感染高危因素者如高龄、 糖尿病、免疫功能缺陷者等）比较两组切口感染及愈合情况。结果：两组患者的自然状况（例数、性别、年龄、手术时间）比较无统计学差异 （P0.05）；两组患者感染率、伤口引流时间及住院时间比较差异均无统计学意义（P0.05）。结论：甲状腺清洁手术应用抗生素并不优于不应用抗生素，也不会增加手术伤口感染率，为预防术后切口感染应用抗生素无实质性必要。 　　【关键词】甲状腺；手术；抗生素；切口感染 　　【中图分类号】R956 【文献标识码】A 【文章编号】1004-7484（2013）05-0569-02 　　Thyroid the clean surgery whether application Retrospective analysis of antibiotics 　　【Abstract】Objective：Clean hands antibiotics or not thyroid infection and healing of the incision.Method： Patients with thyroid diseases were invested in this research ，all of them had thyroid aseptic operations. The patients were divided into two groups according to whether they had been treated with antibiotics： patients who had not been treated with antibiotics were put into experimental group. Otherwise， the control group. Under condition that patients who had infection factors such as old age， diabetes， immune function defects， etc， should be excluded. Analysis the incision infection rates and healing rates of both groups. Results： Compared with the control group， patients from the experimental group showed no significant difference as to their natural conditions （such as， number， gender， age， operative time） （P 0.05）.Furthermore， there were no significant statistically differences as to the infection rates ，wound drainage time and hospital stay between two groups （P 0.05）.Conclusion： For Thyroid the clean surgeries， non-application of antibiotics neither extend the patients hospital stay and wound drainage time， nor to the risk of infection rate. 　　【Key words】Thyroid gland； Operation；Antibiotics；Infected 　　甲状腺清洁手术是否应用及如何合理应用抗生素缺乏临床研究资料， 抗生素的广泛应用、不合理应用以及滥用，导致细菌普遍耐药以及多重耐药，使得临床治疗失败感染复发，增加了死亡的危险性对人类健康构成了巨大威胁。我们对我院2006年1月～2012年11月共1165例行甲状腺清洁手术的甲状腺患者应用抗生素与否分组，进行回顾性对比分析，现报道如下。 　　1 资料与方法 　　1.1选取2006年1月～2012年11月间我院普外科收治的患者，年龄20～69岁，同时排除患糖尿病、免疫功能低下、营养不良以及术前存在感染的患者，总共选取1165例患者。 具体资料如下： 　　观察组：共230例，男53例，女177例，年龄20～69岁，平均42.3