孟鲁司特在小儿慢性咳嗽诊疗中的效果观察.docVIP

孟鲁司特在小儿慢性咳嗽诊疗中的效果观察 　　[摘要] 目的 观察应用孟鲁司特治疗小儿慢性咳嗽的效果。 方法 随机抽取我院儿科慢性咳嗽患儿116例，均分为对照组和实验组。对照组患儿接受常规治疗，实验组患儿在其基础上接受孟鲁司特治疗。 结果 对照组患儿接受常规治疗后有31例痊愈，约占53.45%；实验组患儿接受孟鲁司特治疗后有49例治愈，约占84.48%。实验组治疗效果明显好于对照组，两组比较，差异有统计学意义（P0.05）；与治疗前相比，观察组和对照组患者治疗后的FEV1、PEF均有明显增加，而IgE明显降低，治疗后观察组与对照组各项指标比较差异有统计学意义（P0.05）。 结论 孟鲁司特在治疗小儿慢性咳嗽诊疗中有很好的效果，大大提高治愈率，适合在临床上推广。 　　[关键词] 孟鲁司特；慢性咳嗽 　　[中图分类号] R725.6 [文献标识码] B [文章编号] 1673-9701（2013）32-0148-02 　　Effect of montelukast in the treatment of children with chronic cough 　　TAO Qiuying 　　Department of Pediatric Internal Medicine， Central Hospital of Zhumadian City in Henan Province， Zhumadian 463000， China 　　[Abstract] Objective To observe the effect of montelukast in the treatment of children with Chronic Cough. Methods A total of 116 cases of children with chronic cough in our hospital pediatric were randomly selected， they were divided them into control and experimental group equally. Children in the control group were given conventional therapy， while children in the experimental group were given montelukast on this basis. Results After being treated by conventional therapy， 31 cases in the control group were cured， occupied about 53.45% of the total. After being treated by montelukast， 49 cases in the experimental group were cured， occupied about 84.48%. The effect of the experimental group was better than that of the control group， the difference was statistics significant （P0.05）. Compared with before treatment， the observation group and control group after treatment， FEV1 and PEF of patients were significantly increased， and IgE reduced significantly， the indicators differences between two groups after treatment were statistically significant （P 0.05）. Conclusion Montelukast has good effect in the treatment of children with chronic cough， it can raise cure rate， so is suitable for popularizing in the clinical. 　　[Key words] Montelukast； Chronic cough 　　慢性咳嗽是常见的呼吸系统疾病，临床表现为咳嗽而无明显肺部疾病。儿童由于易过敏且抵抗力低下尤其易受慢性咳嗽困扰[1]。小儿慢性咳嗽主要原因有过敏性鼻炎、呼吸道感染、环境污染、