经支气管镜下局部化疗治疗中央型肺癌的疗效分析.docVIP

经支气管镜下局部化疗治疗中央型肺癌的疗效分析 　　[摘要] 目的 本研究就经支气管镜下局部化疗应用于中央型肺癌治疗中的临床价值进行了浅显的研究和探讨，从而为临床上提供可靠的数据。 方法 选择我院自2012年1月～2014年1月收治的中央型肺癌患者70例，作为研究对象将其平均分为观察组和对照组，两组患者均35例，观察组行经支气管镜下局部化疗，对照组行全身静脉化疗，在经过一个疗程的治疗后，对两组患者的气道狭窄治疗效果，不良反应发生率及生活质量评分进行观察和统计。 结果 观察组的35例患者接受经支气管镜下局部化疗后的临床总有效率为97.14%；对照组的35例患者接受全身静脉化疗后的临床总有效率为82.86%，差异有统计学意义（P0.05）；接受经支气管镜下局部化疗治疗期间共发生不良反应1例，占5.71%；对照组的35例患者接受全身静脉化疗治疗期间共发生不良反应8例，占22.86%，差异有统计学意义（P0.05）；生活质量评分明显高于对照组35例接受全身静脉化疗后的生活质量评分（P0.05）。 结论 经支气管镜下局部化疗应用于中央型肺癌治疗中的效果显著，有效改善了患者的生活质量，值得推广。 　　[关键词] 中央型肺癌；支气管镜；局部化疗；静脉化疗；临床价值 　　[中图分类号] R734.2 [文献标识码] A [文章编号] 2095-0616（2015）14-13-04 　　Analysis of curative effects of local chemotherapy under bronchoscopy in the treatment of central lung cancer 　　LIAO Quanzhong ZENG Jiechang CUI Jian YANG Quan 　　Conghua Central Hospital， Cuangzhou 510900， China 　　[Abstract] Objective To research and explore the clinical value of local chemotherapy under bronchoscopy in the treatment of central lung cancer so as to provide reliable data for clinic. Methods 70 patients with central lung cancer in our hospital who were admitted to our hospital from January 2012 to January 2014 were selected as the research objects and they were allocated to the observation group and the control group， with 35 in each. The observation group was received local chemotherapy under bronchoscopy while the control group was received systemic chemotherapy. After treatment of a course， curative effects of airway stenosis， the incidence rate of adverse reactions and score of life quality of patients in two groups were observed and recorded. Results The total clinical effective rate of 35 patients in the observation group who were received local chemotherapy under bronchoscopy was 97.14% while the total clinical effective rate of 35 patients in the control group who were received systemic chemotherapy was 82.86%. The difference of two groups was significant （P 　　[Key words] Central lung cancer； Bronchoscopy； Local chemotherapy； Systemic chemotherapy； C