ppt课件-do d influenza surveillancefor v r b p a c（做d流感surveillancefor v r b p c）.pptVIP

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2017-01-25 发布于四川
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ppt课件-do d influenza surveillancefor v r b p a c（做d流感surveillancefor v r b p c）.ppt

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18 Feb 2004 18 Feb 2004 18 Feb 2004 Topics to be Covered Existing surveillance programs (overview) Data available for evaluation of VE Navy VE estimate (recruit centers) Army VE estimate (Ft. Lee outbreak) AF VE estimate (phone survey, underway) Existing Surveillance Programs-AF Existing Surveillance Programs-Navy Existing Surveillance Programs-Army ILI Activity Data Sources ILI Activity Data Sources Local public health officer reports Data Sources (cont’d) Local public health officer reports Coded ambulatory visits ESSENCE “DNBI” Data Sources (cont’d) Local public health officer reports Coded ambulatory visits ESSENCE “DNBI” Laboratory results Surges from a site Unusual results Data Sources (cont’d) Local public health officer reports Coded ambulatory ESSENCE “DNBI” Laboratory results Surges from a site Unusual results Immunization data Individual level NHRC VE Data Existing data from surveillance program Trainees at 4 training bases December 2003 Influenza culture positives only Person-time analysis Weeks at risk Vaccinated vs. unvaccinated (2 wks post vax) Basic trainees are vaccinated upon arrival NHRC data (cont’d) VE calculation AR vax = 4 cases / 54278 person-wks 7.37/100,000 person-wks AR unvax = 15 cases / 18617 person-wks 80.6/100,000 person-wks RR = 7.37 / 80.6 = 0.0914 VE = 1 – RR = 90.9% Ft Lee, Virginia US Army post - Quartermaster Training 3,200 trainees; courses of varying length; 12%/week turnover Influenza outbreak, 31 Oct-11 Nov 2003 Ft. Lee ILI Epi Curve Ft Lee, Virginia US Army post - Quartermaster Training 3,200 trainees; courses of varying length; 12%/week turnover Influenza outbreak, 31 Oct-11 Nov 2003 PH response: mass immunization, case isolation Vaccine Effectiveness Study Attempt 2 cohorts “tight” and “loose” case definition Limitations – temporality, highly immunized population, exhaustion of susceptibles, random mixing assumption VE Results AF IVE Evaluation: Plan A Identify exposed cohort (AF only, not Academy) Index cases: i