硫辛酸联合神经愈痹液腿浴治疗糖尿病周围神经病变患者的临床分析.docVIP

硫辛酸联合神经愈痹液腿浴治疗糖尿病周围神经病变患者的临床分析 　　[摘要] 目的 分析硫辛酸联合神经愈痹液腿浴治疗糖尿病周围神经病变患者的临床效果。 方法 选取我院2014年5月～2015年12月81例糖尿病周围神经病变患者，参照随机数字表法将其随机分为A组（40例）和B组（41例），所有患者均给予常规降糖治疗，控制血糖水平，另外A组加用硫辛酸治疗；B组加用硫辛酸联合神经愈痹液腿浴治疗。比较两组总有效率，不良反应发生率，治疗前后患者感觉神经、运动神经传递速度、空腹血糖、餐后2 h血糖和糖化血红蛋白等。 结果 A组总有效率为75.00%，B组总有效率为95.12%，B组明显高于A组，差异有统计学意义（χ2=10.223，P=0.000）。治疗前两组空腹血糖、餐后2 h血糖和糖化血红蛋白接近，差异无统计学意义（P0.05）；治疗后B组空腹血糖、餐后2 h血糖和糖化血红蛋白更佳，差异有统计学意义（P0.05）；治疗后B组感觉神经、运动神经传递速度更佳，差异有统计学意义（P0.05）。 结论 硫辛酸联合神经愈痹液腿浴用于糖尿病周围神经病变患者的临床治疗效果确切，值得推广。 　　[关键词] 硫辛酸；神经愈痹液腿浴；糖尿病周围神经病变患者；治疗效果 　　[中图分类号] R587.2 [文献标识码] A [文章编号] 1674-4721（2016）05（b）-0124-03 　　[Abstract] Objective To analyze the clinical effect of lipoic acid combined with nervous recovery liquid leg bath in treating diabetic peripheral neuropathy. Methods 81 diabetic peripheral neuropathy patients from May 2014 to December 2015 of our hospital were selected and were divided into A group （n=40） and B group （n=41） according to random number table.All patients were given routine hypoglycemic therapy and control glucose level.Apartment from that，patients in A group were further given lipoic acid and patients in B group were given lipoic acid combined with nervous recovery liquid leg bath.The total effective rate，incidence rate of adverse effects，the difference of sensory nerve，motor nerve transfer speed，fasting blood glucose，hplasmaglucose and glycated hemoglobin before and after treatment in two groups were compared. Results The total effective was 75.00% in A group，less than that was 95.12% in B group，and the difference was statistically significant （χ2=10.223，P=0.000）.The fasting blood glucose，2 h plasma glucose and glycated hemoglobin before treatment in two groups were equal，and the differences had no statistical significance （P0.05）；after treatment，the fasting blood glucose，2 h plasma glucose and glycated hemoglobin before treatment in B group were better than A group，and the differences were statistical significance （P0.05）.After treatment，sensory nerve and motor