碳纳米管及其复合材料在生物医学领域的研究进展.pdfVIP

物医学工程学杂志 2006 】BJ ；23(2)I 438～44l oined Eng ‘ ’ 、 … … 碳纳米管及其复合材料在生物医学 领域的研究进展* 郭小天综述 许海燕△审校 (中国医学科学院 中国协和医科大学基础医学研究所，北京 100005) 摘要 碳纳米管是一种新型碳材料，具有特殊的纳米结构和优异的力学、电学和磁学性能，在生物医学领域显 示出诱人的潜在应用价值和前景，吸引了越来越多的研究者的关注。本文简要介绍了碳纳米管的基本结构与性能， 并对近年来碳纳米管在生物大分子的修饰与特异性识别、细胞体外生长支架、植入性生物医学材料、生物医学传感 器以及生物医学微电子器件等方面的研究进展和发展趋势进行了综合评述。 关键词 碳纳米管 生物相容性 生物分子 细胞生长 生物传感器 Research and Development of Biomedical Application of Carbon Nanotubes and Related Composites Guo Xiaotian Xu Haiyan (Institute of Basic Medicine，Chinese Academy o}Medical Sciences Peking Union Medical College，Beifing 100005，China) Abstract Carbon nanotubes，a new member of the carbon material family，can be considered as graphite sheets rolled—up into cylinders with diameters ranging in the nanometer scale．In recent years，carbon nanotubes have attracted intensive interests because of their unique nanostructures and outstanding mechanical，electrical and magnetic properties．In this paper，the structures and basic features of carbon nanotubes were described in brief． The research advances in the carbon nanotubes on the specific recognition of biomolecules by surface modification and functiOnaIizatiOn，in the enhancement tO cell growth as culture scaffolds in vitro，and in the improvement of biocompatibility for implantable biomedical material were reviewed．Also comments were made on their potential applications in biomedical sensor and biomedical microelectrics． Key words Carbon nanotubes Biocompatibility Biomolecules Cell growth Biosensor 1 引 言 发展趋势进行综述和探讨。 2 碳纳米管的基本结构和性能 碳纳米管(Carbon nanotubes)具有独特的结构 和物理化学性质，如低密度、高比模量、高强度、良好