1 case of outpatient oral hypoglycemic agents induced hypoglycemic coma reported.docVIP

 PAGE \* MERGEFORMAT 4 1 case of outpatient oral hypoglycemic agents induced hypoglycemic coma reported [Keywords:] low blood sugar, coma, hypoglycemic agents Hypoglycemic drug glibenclamide because of effective, low prices are widely used in clinical treatment of type 2 diabetes, but serious side effects that cause low blood sugar coma. Hypoglycemic coma is a common life-threatening emergency door health disease, its clinical manifestations complex, more performance for the palpitations, sweating, hunger, dizziness, irritability and then a coma. early detection, early treatment and intensive care is especially important for the prognosis of patients. In this paper, our hospital October 17, 2009 1 out- patients taking glibenclamide treatment were caused by low blood sugar coma case analysis aimed at improving the understanding of this disease. 1 Clinical data Patients, male, 65 years old, history of diabetes. On October 17, 2009 when the clinic accompanied by palpitations, sweating, hunger, dizziness, irritability and then a coma. Because of the amount of patients with conventional treatment before taking glibenclamide, To be considered for the oral hypoglycemic agents, hypoglycemic coma, hospitalized after 1.5 h the onset of observation, not by head CT revealed high density lesions, checking blood glucose below 1.6 mmol / L, normal electrolytes, urine sugar and ketone bodies were negative. 2 Treatment and outcome Diagnosis 50% immediately after the intravenous injection of glucose solution 50 ~ 100 mL, pushing drugs in patients after 15 ~ 30 mL clear, 15 min after the Q amp; A to the point, can be self-limbs, every 1 2 h monitoring of blood glucose, and continue to give 5 % ~ 10% glucose solution by continuous intravenous infusion 24 ~ 48 h, for the prevention of recurrent disease, when blood sugar is less than 4.5 mmol / L again 50% glucose solution intravenously 40 mL. after 3 fasting blood glucose stabilized at 5.0 ~ 10.7 mmol / L after di