Aging changes when the body index.docVIP

 PAGE \* MERGEFORMAT 13 Aging changes when the body index Of: Zhao Yanyan Liu Xinxia Chen Chunsheng Tian Fang Peng Lu Cuiyan Long Qiu [Keywords] aging, biochemical and histological change, changes in the body index, the immune system, nervous system, brain-derived neurotrophic factor, thyroid hormones, free radicals, anti-peroxidase system, telomerase, nitric oxide (NO) Aging is the body in the degradation period of tissues and organs physical function decline and physical disorders and overall performance, is the body inherent in complex, irreversible process. In the study found that aging body when not only the exterior changes, the body has undergone many biochemical , and histological changes, this paper aging occurs when the body inside an overview of these changes for the aging study provides clinical data. An immune system changes with aging Important to the immune system is the body defense system, the immune organs, immune cells and immune factors and other components, for the pathogens to resist against the outside world, maintaining the normal function of organs and tissues of the body play an important role. Senescence of immune function and the close links between , the immunological theory of aging that is caused by the decline of immune function in the body an important factor in aging. As the aging process, reduce immune system function, immune organs, immune cells and immune factors such as a lot of changes, by improving the immune system then can delay the aging process. Experimental studies have shown (1,2), aging thymus and spleen weight, thymus index decreased, increased thymocyte apoptosis, T lymphocyte proliferation rate decreased lymphocyte transformation rate decreased, reducing the number of peripheral white blood cells, antibody-secreting reduction, cell interleukin 2 (IL 2, serum thymic factor (IFN , tumor necrosis factor (TNF) in the 3 T helper cell 1 (TH1 type cytokines decrease the activity of peritoneal macropha