Allicin treatment of viral myocarditis.docVIP

 PAGE \* MERGEFORMAT 14 Allicin treatment of viral myocarditis Study: Pan Xingshou, blue Jingsheng, Li talent, according to Huang River, Liu Yan, Liang Ye, Lai Tengfang [Abstract] Objective To observe glutathione on cardiopulmonary bypass (CPB) during interleukin-8 (IL 8) and interleukin 6 (IL 6) the impact. Methods 30 patients underwent cardiac surgery were randomly divided into experimental group and control group (n = 15). experimental group were given at the beginning of the operation of glutathione (35 mg / kg) dissolved in 100 ml normal saline infusion, intravenous infusion of normal saline control group. in before CPB (T1), CPB 30 min (T2), CPB shutdown (T3), shut down after 2 h (T4) four time points blood samples, were measured by radioimmunoassay in serum IL 8 and IL 6 concentrations. Results experimental group, IL 8, IL 6 serum concentrations lower than the control group, the difference was statistically significant (P lt;0.05). Conclusion glutathione during CPB can reduce IL 8 and IL 6 release, reduce the systemic inflammatory response level. [Keywords:] glutathione; cardiopulmonary bypass; inflammatory response syndrome; interleukin-6; interleukin-8 [Abstract] Objective To investigate the effects of glutathione (GSH) on interleukin 8 (IL 8) and interleukin 6 (IL 6) during cardiopulmonary bypass (CPB). Methods Thirty patients undergoing Cardiac surgery were randomly divided into GSH group and control group ( 15 in each group). In GSH group, intravenous drip of 100 ml of GSH (35 mg / kg) was given at the beginning of surgery. Respectively, while the control group was given 0.9% NaCl solution.Blood samples were taken before CPB , 30min after CPB and 0h, 2h after the end of CPB. The serum levels of IL 8 and IL 6 were measured by radioimmunoassay method in both groups.Results The serum levels of IL 8 and IL 6 in GSH group were significantly lower than that in control group (P lt;0.05). Conclusion The study shows that GSH could reduce the rele