Chinese influence factors of safety.docVIP

 PAGE \* MERGEFORMAT 27 Chinese influence factors of safety [Keywords:] traditional Chinese medicine safety, influence factors, review Change as the disease spectrum, the arrival of an aging society and the many drawbacks of chemical drugs emergence on the world, including Chinese traditional medicine, including a re-evaluation and re-start awareness of the scope of application of Chinese medicine also will be more and more widely. It is in this context, the safety problems of Chinese medicine is also increasing year by year, security has become one of the bottlenecks restricting the development of Chinese medicine. Factors Affecting the basis of safety studies is part of how adverse reactions from traditional Chinese medicine in the search for the reason, is an important aspect of safety studies. The author is from the influence of specific factors that both the content and methods of Chinese medicine on the current Review of safety factors as follows. 1 factors 1.1 Drugs 1.1.1 Chemical composition The adverse reaction of traditional Chinese medicine contains chemicals that may be related to pharmacological effects and are closely related. Such as licorice with the proposed role of adrenal cortical hormone-like substances can cause edema, hypokalemia, hypertension, malaise and other adverse reactions and even lead to metabolic alkalosis, North Wujiapi contain toxic ingredients cardiac glycosides, cows cows contains sub-sub-glycosides, can stimulate the renal injury, acute renal failure, Hill arrowhead with colchicine, rapid oxidation in the body into the oxide Colchicine, a highly toxic, on the urinary system has severe irritation and damage [1]. State has already identified 28 kinds of toxic Chinese medicines, including herbal medicine, such as raw Pinellia, raw Southern Star, Aconitum head, Croton, henbane, etc., in animals, such as Toad, cantharidin, blue lady, red lady, etc., mineral classes such as arsenic , mercury, realgar, Pink