Chronic obstructive pulmonary disease with acute exacerbation of application of noninvasive positive pressure ventilation efficacy.docVIP

 PAGE \* MERGEFORMAT 10 Chronic obstructive pulmonary disease with acute exacerbation of application of noninvasive positive pressure ventilation efficacy [Keywords:] chronic obstructive pulmonary disease Noninvasive positive pressure ventilation According to the literature [1], noninvasive positive pressure ventilation (NIPPV) for chronic obstructive pulmonary disease with acute exacerbation (AECOPD) due to respiratory failure (referred to as respiratory failure) have made positive effect, compared with conventional treatment, NIPPV for the treatment of AECOPD the success rate of up to 80% to 85%, but for the effect of severe respiratory failure, use the time remaining in the larger controversy [1 ~ 4]. NIPPV treatment in our hospital in respiratory applications, 41 cases of severe respiratory failure, The results showed that the situation observed in patients with ventilation and blood gas parameters were significantly improved. 1 Subjects and methods 1.1 The choice of cases reviewed in our department in May 2007 ~ October 2008 41 patients were admitted in respiratory failure due to AECOPD were included in the study, renal function was normal, we have pH values #8203;#8203;of ≤ 7.25 determined under severe respiratory failure, 7.25 1.2 Treatment Elisee150 positive airway pressure ventilation (PSV) initial ventilator inspiratory pressure (P Insp) 8 ~ 10 cm H2O (1 cm H2O = 0.098 kPa), positive end expiratory pressure (PEEP) 0 ~ 3 cmH2O, in 10 min, increased to treatment parameters, observed significant improvement in ventilation, adjust the oxygen flow to blood oxygen saturationgt; = 90%. multifunction ventilator to pressure support ventilation (PSV) or synchronized intermittent mandatory ventilation (SIMV) , select the appropriate support for pressure to maintain tidal volume (VT)gt; 400 ~ 500 ml. In addition to the daily life of 3 d before and sputum, but continued on the machine, after a day on the machine to keep 6 ~ 8 h. If the ventilation in