Enzymatic bio-active ingredients of Chinese medicine into.docVIP

 PAGE \* MERGEFORMAT 20 Enzymatic bio-active ingredients of Chinese medicine into [Abstract] reviewed the profile of enzymatic biotransformation and glycosidic enzymes, oxidoreductases, and other groups biotransformation enzyme hydrolysis of the transfer of effective components of Chinese medicine progress. [Keywords:] Biotransformation; enzyme; medicine; active ingredients Bioconversion (biotransformation) is the use of isolated cells or organs of plants, animal cells, microorganisms and their organelles, and the free enzyme to exogenous compounds (exogenous substrate) structural modification of the biochemical reactions. Its essence is the use of biological systems produced by itself exogenous enzyme catalyzed reaction of compounds, it has the reaction selectivity, mild reaction conditions, less by-products, not to cause environmental pollution and post-processing and simple. The earliest human use of biological control and conversion technology is the wine and vinegar. In the ancient wine and vinegar are also used as a drug of Louis Pasteur discovered .1864 oxidation of ethanol to acetic acid bacteria can, humans began to use microbial transformation method for the synthesis of chemical substances. using sorbitol oxidation of acetic acid bacteria, such as weak and A.melangenum A.suboxydans into the role of optically active L-sorbose (L-sorbose is the key intermediate of vitamin C synthesis) [1], which A microbial transformation method enables large-scale industrial production of vitamin C can supply a large number of clinical applications, change the people in the past can only be contained in fruits and vegetables, vitamin C to treat trace the situation of the disease. In recent years, with genetic engineering, enzyme engineering, cell engineering technology continues to develop and improve, so that bio-conversion technology is widely used in structural modification of natural and synthetic compounds, the conversion of prodrug compounds, organic