External application of Chinese medicine on gastrointestinal Xiaoji San kinetics.docVIP

 PAGE \* MERGEFORMAT 9 External application of Chinese medicine on gastrointestinal Xiaoji San kinetics [Abstract] Objective To investigate the external application of Chinese medicine powder negatively impact on the gastrointestinal motility. Methods (1) take 18 ~ 22 g mice 30 were randomly divided into three groups, measuring its length and the carbon front end of the distance to the cardia to calculate the percentage with full-length, namely, promoting the percentage; (2) take a dolphin Organization of rat jejunum (about 3 cm), gut ligation at both ends with the line, one end of the ventilation system on the hook, the placed filled with Tyrode’s solution of the Maxwell bath, which leads to the volume fraction of 0.05 with the CO2 to oxygen, water bath temperature to (35.0 ± 0.1) ℃ , the other end tied load of about 2 g of the transducer, the connecting recorder to observe the intestinal smooth muscle to normal movement of the three kinds according to different order of administration, painted in mind its waveform; (3) Wistar 30 rats. The experimental group 10, using powder applied externally rather negatively in rats Shenque Point and Zhongwan Point; Spleen group of 10, with the same period in the experimental group for modeling bio-electrical detection of gastrointestinal, but without any drugs; control group: normal big Rat 10, the same period in the previous two groups was detected by gastrointestinal bioelectric. Results (1) to 0.1 g / plot just by giving mice abdominal bulk medication 5 d, which indicates that a very significant role in the enhanced gastrointestinal propulsion; (2) negatively not only on the normal isolated, scattered smooth muscle relaxing effect, while as Acetylcholine, barium chloride induced spasm intestinal smooth muscle spasm is also a strong role, the experiment is 10 μ g atropine sulfate as a positive control drug to control experiments, demonstrating the role of graphic spasm of atropine sulfate; (3) Xiaoji San Umbilicus righ