FDP crisis of acute cases of hyperphosphataemia.docVIP

 PAGE \* MERGEFORMAT 4 FDP crisis of acute cases of hyperphosphataemia Of: Fu Zhaohua, Lvhui Qi, Li Ping, Zhang Fourth Army [Keywords:] FDP; Acute hyperphosphatemia; Analysis Acute hyperphosphatemia crisis is a serious life-threatening electrolyte imbalance, can cause a number of related clinical manifestations. Undergraduate recent application of 1 case treated after FDP acute hyperphosphatemia are reported below. 1 Case information Patients, male, 68 years old. Because of “4 days after cholecystectomy, no urine 2 days” into the course by the Department of General Surgery. Past 15 years, history of hypertension, coronary heart disease 4 years. Preoperative normal renal function investigation, surgical procedure more smoothly. Postoperative FDP (Guorui Pharmaceutical Company) intravenous infusion of 10g bid, shared 5 times, 6 days after operation there oliguria, anuria, with nausea, vomiting, diarrhea, hand-foot-jitter, chest tightness, and decreased visual acuity, Jicha renal function: Cr 556.7mol / L, BUN 27.26mmol / L, Ca 1.3mmol / L, P 6.9mmol / L, WBC 1.6 109 / L, PLT 96 109 / L, diagnostic acute hyperphosphatemia and acute renal failure. to hemodialysis treatment for 3 days, serum phosphorus decreased to normal urine output gradually increased after 1 week, but no significant improvement in renal function, serum Cr 347.75 ~ 721.25mol/L.2 weeks after the general situation improves, went to Wuhan Tongji Hospital of the kidney biopsy, the pathological diagnosis of acute tubulointerstitial nephropathy. 2 Discussion FDP is a product of the body’s cellular metabolism, glucose metabolism can regulate the activity of various enzymes. The T1 2 is about 12 ~ 15min, hydrolysis of inorganic phosphate and fructose, inorganic phosphorus excretion by the kidneys 90%, 10% by intestinal tract. Hyperphosphatemia can occur in a variety of diseases, common in renal phosphorus discharge reduction or excessive intake of exogenous phosphorus, such as r