Fluoroquinolones should be standardized for children.docVIP

 PAGE \* MERGEFORMAT 15 Fluoroquinolones should be standardized for children 【Abstract】 Objective: To quinolones in children with problems in the application were discussed. Methods: The literature was reviewed, the more the authority of the newly published monograph of medicine and drug brochures on the use of quinolones for children to compare the safety warning, combined with our hospital for children’s use of quinolones were analyzed. Results: The application of these drugs for children, short-term, there may be rash, nausea, headache symptoms and no long-term impact of child development. Drug statement relating to the safety warning for children there is inconsistency, be standardized. Conclusion: Children should be used with caution in patients with clinical quinolone drugs should be used with trade-offs, and make follow-up. Keywords: quinolone; children; Security Quinolones and other antimicrobial drugs the difference lies in the role of the bacterial DNA as a target, it can inhibit DNA enzyme turn impede DNA synthesis, resulting in irreversible damage to bacterial chromosome leading to bacterial death. This kind of selective bacterial toxicity, determines that it does not have to many antimicrobial agents cross-resistance. In recent years, with the quinolones and constantly develop new products, further expand the antimicrobial spectrum, clinical applications are more extensive. In my hospital, the number and type of drug use compared to other antibacterial drugs, among the best. However, such drugs in the clinical application of the process, children with drug safety issues remain the focus of attention. An analysis of drug use in our hospital Quinolones 1.1 General Information 2005 total annual discharge passengers 1 125 cases, of which 632 cases of male and female 493 cases, 748 cases suffering from infectious diseases, accounting for 66.5% of the total number of cases. Which contained the