Fluoroquinolone antibiotic adverse drug reactions and clinical application of.docVIP

 PAGE \* MERGEFORMAT 4 Fluoroquinolone antibiotic adverse drug reactions and clinical application of [Keywords:] fluoro-quinolone antibacterial clinical application of adverse drug reactions Fluoroquinolones (fluoroquinolone) drugs with a broad-spectrum, efficient, safe, convenient features, widely used in clinical practice, but with a large number of clinical applications, such adverse drug reactions reported more and more. To this end, this article reports on fluoroquinolones adverse reactions and clinical applications and reasonable to do a brief description in order to enhance clinicians to fluoroquinolones awareness of adverse drug reactions and improve the level of clinical rational drug use. A fluoroquinolone drugs and clinical applications of Fluoroquinolone drugs norfloxacin, ciprofloxacin and ofloxacin, etc. In recent years, the development of levofloxacin, gatifloxacin, pefloxacin and moxifloxacin and other raised against Gram-positive bacteria and atypical pneumonia type pathogen antimicrobial activity, but also gradually used clinically. 2 fluoroquinolones adverse drug reactions (ADR) 2.1 fluoroquinolones digestive reaction was the most common adverse reactions, mainly gastrointestinal disorders, symptoms are nausea, vomiting, abdominal pain, abdominal discomfort, each fluoroquinolone tolerance of the gastrointestinal tract had no significant differences in oral majority, the general self-healing after drug withdrawal. 2.2 The central nervous system (CNS) response to fluoroquinolones central reaction is the second common adverse reactions, common symptoms include headache, dizziness, insomnia, lack of clarity depending on materials. Severe can cause paranoia, coma, convulsions, tremors, seizures or depression. HOU Ai-dong et al [1] reported 1 case, female, 43 years old, patients with intravenous infusion of 0.2% Gatifloxacin Glucose Injection 200ml, medication to 90ml when chest tightness, nausea, there will be intended, depending on the mat