Flurbiprofen combined sufentanil for postoperative analgesia in esophageal cancer.docVIP

 PAGE \* MERGEFORMAT 12 Flurbiprofen combined sufentanil for postoperative analgesia in esophageal cancer Of: Zhang Ni, Kangzhen Ming, Shu Jinjun [Abstract] Objective To observe the thoracic esophageal cancer surgery after the application of flurbiprofen combined with sufentanil controlled intravenous analgesia and safety. Methods 60 patients undergoing elective (preoperative ASA I ~ grade esophageal chest tumor resection patients, randomized double-blind method is divided into control group, small dose group and flurbiprofen axetil and sufentanil combined treatment group (combination group), 20 cases each. respectively after 6, 12,24,48 h observation of the patient’s VAS score (visual analogue scale, Prince Henry score, analgesic consumption (CAC), sedation score, side effects (nausea, vomiting, respiratory depression, etc.), and in the preoperative, intraoperative completion of the measurement of plasma cortisol at all time points (Cor) value. Results in control group compared with the combined treatment group, postoperative 6,12,24,48 h VAS score, Prince Henry score, CAC, and there was no difference compared Cor value statistically significant (Pgt; 0.05, and the control group, the combined treatment group are less than the above low-dose group (P lt;0.05), low dose group and 48 h after the combination group of nausea and vomiting were significantly less than the control group (P lt;0.05). Conclusion flurbiprofen sufentanil for thoracotomy combined resection of esophageal cancer controlled intravenous analgesia can reduce the amount of sufentanil and the larger dose of simple analgesia Shufen quite fentanyl, and postoperative stress response, nausea, vomiting lower than a simple application of sufentanil. [Keywords:] flurbiprofen sufentanil analgesia after surgery thoracic surgery in esophageal cancer Because esophageal cancer resection thoracotomy surgical trauma, severe postoperative pain, postoperative analgesia can effectively increase deep