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Fluoxetine treatment of depression after stroke Clinical Observation
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Fluoxetine treatment of depression after stroke Clinical Observation
[Keywords:] stroke; depression; fluoxetine; amitriptyline; effect
[Abstract] Objective To investigate the fluoxetine in the treatment of post-stroke depression clinical efficacy. Methods 90 patients with post-stroke depression in patients 50 patients were randomly divided into study group and control group of 40 patients, two groups of conventional treatment and psychological treatment of stroke, based on the research team combined with fluoxetine treatment in the control group for the joint-Ami lin treatment, observation 3 w. In the treatment of 3 w before the end of treatment using Hamilton Depression Rating Scale assessment of clinical efficacy. Results The total effective study group 92.0%, 67.5% of the control group, the difference was significant (P amp;lt;0.05). Conclusion fluoxetine in the treatment of clinical depression after stroke is superior to amitriptyline treatment.
[Keywords:] stroke; depression; fluoxetine; amitriptyline; effect
Stroke is harmful to life and health in old age, one of major diseases, post-stroke depression (postroke depression, PSD) is a common complication of cerebral vascular accident [1], seriously affect the function and activities of daily living in patients with neurological recovery. China has reported in the literature [2] The incidence was 31.2%, the active treatment PSD, improving the patient’s quality of life significance. The author of fluoxetine and amitriptyline in patients with PSD conducted a controlled observation, is reported as follows.
1 Data and methods
1.1 General information on the sample taken from 1998 to 2004 in our hospital 320 cases of acute stroke patients. Into the group of standards: (1) diagnosis of stroke are in line with 1995 ‘Fourth National Conference on Cerebrovascular Diseases’ established diagnostic criteria for stroke [3], and confirmed by head CT; (2) depression are in line with’ China menta
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