Formation Mechanism of bitter taste masking bitter taste and Traditional Chinese Medicine Research Technology.docVIP

 PAGE \* MERGEFORMAT 18 Formation Mechanism of bitter taste masking bitter taste and Traditional Chinese Medicine Research Technology Authors: Zheng-Gen Liao, Wen-Jing Zhong, Jiang and the United Kingdom, Yang Ming [Abstract] based on the formation mechanism of bitterness, from interfering with the formation of the different segments of the bitter medicine taste masking bitter taste correction techniques include adding agents, confuse the brain bitter taste mask drugs; slow or prevent the release of drugs in the oral cavity, isolation of drugs and taste buds of the contacts; paralysis of taste cells, improve the bitter taste perception threshold; to prevent a bitter taste receptor in combination with the bitter agent to cut off the signal transduction mask bitterness and other four categories, review the method to cover up bitter medicine, and to outline the advantages and disadvantages of various methods and preparation techniques, reasonable application of bitter taste masking technology to provide theoretical guidance. [Keywords:] bitter formation mechanism; bitterness; taste masking technology Abstract: According to the mechanism of bitter formation, the bitter taste masking technology is classified into different sorts from different taches that disturb the bitterness formation, include adding the taste correcting substance to confuse the cerebral taste; staving or preventing the drug releasing in mouth and segregating the contact between drug and taste buds; anesthetizing the taste cell to enhance the threshold of bitter taking; preventing bitter taste receptor combining with bitter blocker, cutting off the signal transduction pathways etc.Summerize the methods of taste masking technology, besides, describe the method’s advantages and disadvantages, and the technology of preparation.Provide academic direction for the reasonable use of bitterness taste masking. Keywords:: Mechanism of bitter formation; Bitterness; Taste masking technology Bitter, is