From 2004 to 2005 in our hospital clinical surveillance of antimicrobial resistance commonly.docVIP

 PAGE \* MERGEFORMAT 20 From 2004 to 2005 in our hospital clinical surveillance of antimicrobial resistance commonly Authors: Zhuo Chao Wen-Xiang Huang Zheng-line Chongzhi Xia Du Yu-ping-ping 【Abstract】 Objective To investigate the surveillance of antimicrobial resistance in China to help group (CHINET) Working Group in Chongqing in November 2004 ~ November 2005 on a variety of common clinical bacterial antimicrobial resistance status quo. Method of drug susceptibility testing using disc diffusion method, drug resistance data analysis software used WHONET5. The results of a year for the first time in our hospital were collected from patients with isolates 1380; Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, Acinetobacter baumannii, coagulase-negative staphylococcus, Staphylococcus aureus, Enterobacter Enterobacter, and Enterococcus faecalis were the most common bacteria, the respective proportions of 18.6%, 13.6%, 11.3%, 10.0%, 9.4%, 9.1%, 8.0% and 3.9%. Enterobacteriaceae resistant to imipenem and meropenem for the lowest rate, producing extended spectrum β  lactamases (ESBLs) in Escherichia coli and Klebsiella pneumoniae strains detection rates were 37.5% and 31.4%; all strains produced ESBLs were sensitive to imipenem and meropenem, Pseudomonas aeruginosa to imipenem and meropenem resistance rates were 37.2% and 39.4%, to ceftazidime resistance rate of 48.9% , and the emergence of pan-resistance to all drug-resistant strains. Acinetobacter baumannii to imipenem and meropenem sensitive rates were 98.6% and 92.8% to cefoperazone / sulbactam sensitivity rate, intermediate rate, resistance rates were 34.8%, 27.5%, 37.7 %. Drug combination analysis showed that pairs of cefoperazone / sulbactam is not sensitive to strain has 58 for the same resistance patterns, PFGE analysis, these strains mainly from two clone. In addition to carbapenem-sensitive, the other drugs are resistant, of which 46 come from the same ward. Conclusion hospit