High Performance Liquid Chromatography Qingnao of ferulic acid in blood pressure tablets.docVIP

 PAGE \* MERGEFORMAT 7 High Performance Liquid Chromatography Qingnao of ferulic acid in blood pressure tablets [Abstract] Objective: To establish a clear brain blood pressure tablets determination of ferulic acid content. Methods: High performance liquid chromatography, column: C18 (4.6mm * 150mm, 5μ m); mobile phase: acetonitrile -0.085% phosphoric acid (17 ︰ 83); column temperature: 35 ℃ ; detection wavelength: 316nm; flow rate: 1.0ml / min. Results: The method is stable and good reproducibility, high recovery rate, accurate and reliable. Conclusion: This method can serve as a clear determination of cerebral blood pressure tablets approach. [Keywords:] ferulic acid, blood pressure tablets Qingnao high performance liquid chromatography assay Qingnao Jiangyapian income is contained in ‘The 2005 edition of a Chinese Pharmacopoeia, is a skullcap, Prunella, Sophora japonica, Angelica sinensis, Salvia and other traditional Chinese medicine composed of 13 Chinese herbal compound preparation [1]. Clinical use of dizziness caused by hyperactivity of liver yang, Zheng Jian dizziness, headache, items of strong, high blood pressure. Did not develop in the standard assay method, ferulic acid is the active ingredient in Radix Angelica sinensis, one of this article refer to ‘The 2005 edition of Chinese Pharmacopoeia under DangGui a method for the determination and the determination of the method of Angelica in [ 2 ~ 3], by high performance liquid chromatography determination of ferulic acid content of samples, hoping to control the final product quality. An instrument and reagent Instrument: Shimadzu-10AtvP, Zhejiang University, N2000 chromatography workstation, column filler for the 18 alkyl silane bonded silica gel, Diamonsil (diamonds)-C18 (200mm * 4.6mm, 5μ m) (Dumas Company). Drug test; ferulic acid reference substances, the Chinese pharmaceutical and biological products available. Acetonitrile for chromatography pure; other reagents were analytical pure. Two