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HPLCMS in Traditional Chinese Medicine Identification
PAGE \* MERGEFORMAT 9
HPLCMS in Traditional Chinese Medicine Identification
[Abstract] In order to ensure the quality of traditional Chinese medicine, the identification of various modern methods are increasingly being identified in the application of traditional Chinese medicine. Using high performance liquid chromatography - mass spectrometry (HPLC MS) combined with technology, high-HPLC separation of complex samples MS high capacity and selectivity, high sensitivity and molecular weight and structural information can provide the advantages of combining traditional Chinese medicine may be a more comprehensive evaluation of the quality.
[Key Words] high performance liquid chromatography - mass spectrometry, traditional Chinese medicine, identification
Liquid Liquid Chromatography (HPLC MS) is the high performance liquid phase chromatography and mass spectrometry technology in series. HPLC is currently the most effective separation of complex systems analysis tools, because of its instrument automation, higher and higher degree of popularity, Chinese medicine has become one of the most commonly used instruments. MS is a highly sensitive detector, and the characteristics of different compounds, and can be used to resolve some of the structure of unknown compounds. HPLC MS to HPLC separation of high performance and strong MS Structure Determination of features combine to Chinese medicine the rapid analysis of chemical composition provides an important new technology [1].
1 HPLC MS analysis of chemical components in traditional Chinese medicine’s role
By HPLC MS MS analysis of chemical components of Chinese medicine techniques, can be retention times, online UV spectrum, molecular weight and characteristics of a wealth of information structure of debris, with high speed and high sensitivity characteristics, only a simple sample pre- handling or derivatization, especially for low levels should not be isolated or in the separation process is easy to
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