HSAFP for liver cancer and the efficacy of TACE prognostic value of surgery.docVIP

 PAGE \* MERGEFORMAT 3 HSAFP for liver cancer and the efficacy of TACE prognostic value of surgery Authors: Yang Lei Run-Zhou Ni, Ming-Bing Xiao, Li Feng, Lu Cuihua, Guo-Ping Hua [Abstract] Objective To investigate the hepatoma-specific alpha-fetoprotein (HS  AFP) for liver cancer, hepatic artery chemoembolization (TACE) after the clinical efficacy and prognostic value. Methods HS  AFP by polyacrylamide gel electrophoresis (PAGE) with Western blot technique (Western blot) separation and detection. 41 cases of liver cancer patients were treated with TACE serum HS  AFP dynamic observation and analysis of HS  AFP and tumor size and stage as well as the efficacy and survival after TACE relationship. The results of TACE before surgery, HS  AFP positive rate was significantly higher than in tumor ≥ 5cm tumor amp;lt;5cm group, clinical stage Ⅱ a b phase was significantly higher than in stage Ⅰ group. TACE in the treatment efficiency in the HS  AFP-positive group was 4.5% lower than the negative group 73.7% (P amp;lt;0.001). Univariate analysis and multivariate analysis show that after HS  AFP in patients with liver cancer prognosis. Conclusion HS  AFP will help to determine the condition of preoperative liver cancer, liver cancer after TACE of the prognosis of great value. [Keywords:] Alpha-fetoprotein; heterogeneity; hepatocellular carcinoma; prognosis 1 Data and methods 1.1 The clinical data of all cases were in December 2003 ~ May 2004 in Nantong City hospital of liver cancer patients (patients underwent TACE). 34 cases were male and 7 females. Age 35 to 75 years old. Preoperative According to the 2001 Professional Committee of Chinese Anti-Cancer Association of liver cancer staging system developed by [2] The patients in phases, of which 9 cases of stage Ⅰ , Ⅱ a b 32 Li. CT measurement of tumor size according to the maximum diameter of the calculation. Within 2 months after operation in accordance with national common solid tumor efficac