Huang Qi Granules volatile oil extraction and β -CD inclusion process of.docVIP

 PAGE \* MERGEFORMAT 4 Huang Qi Granules volatile oil extraction and β -CD inclusion process of Authors: Zhong, YIN Rong-li, Zhou Shufang, Zhang Dan, Li Yi [Abstract] Objective To investigate the Qi Huang volatile oil particles in the optimal extraction process and the best β -CD inclusion process. Methods The single factor in order to close the oil extraction rate as the evaluation of the indicators; for inclusion yield and volatile oil inclusion rate of the comprehensive evaluation process for evaluating the inclusion of indicators preferred β -CD inclusion process. The results of the best essential oil extraction process as follows: Curcuma 6 times the amount of added water, soaking 12 h, extracted 6 h; inclusion volatile oil from the best process for the introduction of saturated aqueous solution method under normal temperature β -CD and the 6:1 ratio of volatile oil from , water and volatile oil ratio of 60:1, inclusion time was 45 min. Conclusion selected extraction extraction rate, inclusion process reasonable and feasible. [Keywords:] Qi Huang Ke; volatile oil; β -CD inclusion complex; single-factor experiments; orthogonal experiment Abstract: ObjectiveTo study the optimum conditions for the extraction of volatile oil in Qihuang Granule, and for the preparation of their β -CD inclusion compounds. MethodsThe study was carried out with single factor. With the percentages of extracted volatile oil as the target markers, the optimum conditions was determined for extraction of the volatile oil. With the ratio of inclusion and the oiling bearing from the inclusion as the target marker the conditions for including the oils with β -CD were optimized. ResultsThe optimized extraction conditions were: the water was 6 times of the herbs in weight, the herbal medicine of Rhizoma Curcumae should be extracted for 6 h after advanced soaking 12 hours with water. The optimal inclusion conditions were: applying the saturated aqueous solution method, under the nature t