Ischemic brain injury in intracerebral transplantation therapy progress and prospects.docVIP

 PAGE \* MERGEFORMAT 13 Ischemic brain injury in intracerebral transplantation therapy progress and prospects Keywords:: ischemic brain injury in intracerebral transplantation of genetically modified cells, embryonic Abstract brain transplantation has become an impressive neuroscience field, using brain transplantation for treatment of ischemic brain injury in experimental research has gradually attracted people’s attention and was regarded as treatment of ischemic brain injury in promising new ways and new strategies . Genetically modified cells and cell lines transplanted fetal brain transplant because of avoiding the ethical and source of the problem, has become a new hotspot and direction. Thompson first time since the transplant experiment of the cerebral cortex has undergone a brain transplant more than a century of development, has become a neuroscience areas of concern. In recent years, brain transplantation for treatment of ischemic brain injury in experimental studies have been very active and has made great progress [1-3]. In animal experiments, both the fetal brain tissue transplantation or genetically modified cell transplantation, ischemic brain injury in the brain transplant therapy have shown a good efficacy 4-6], for the future clinical application of experimental data has accumulated. Recombinant DNA technology and stereotactic technology, makes the clinical applications in the future could be through the establishment and development of cell lines and cell banks, using stereotactic technology, method, almost no damage to the brain receptors of the multi-target injection of transplantation and repeated transplantation. 1. Fetal brain tissue, cell transplantation An ideal source of donor organizations and has been a brain transplant research important issues. Although in the future treatment of intracerebral transplantation, fetal brain tissue may be due to the source and application of ethical issues is limited [3,7], but a large number o